SAMHSA · 201 centers · Updated May 2026

Find Treatment Centers in South Carolina

201 SAMHSA-verified treatment facilities across South Carolina. 1,380 annual opioid deaths — ranked #15 nationally. Compare programs, check insurance, get connected.

✗ No Medicaid Expansion Naloxone: standing order ✓ Good Samaritan Law
Browse 201 Centers in South Carolina
Talk to a licensed admissions advisor
Free · Confidential · 24/7 (833) 546-3513
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Treatment available in South Carolina

201 SAMHSA-verified centers
Medical detox Inpatient / residential Outpatient MAT Co-occurring (dual dx)
  • Sliding-scale & state-funded options statewide
  • Centers in 30+ South Carolina cities
  • Free, confidential help — available 24/7

Treatment Centers in South Carolina

206 facilities found

All Cities
Greenville (16)
Charleston (11)
Florence (9)
Columbia (8)
Myrtle Beach (6)
Rock Hill (5)
North Charleston (5)
Darlington (5)
Aiken (5)
Sumter (4)
Spartanburg (4)
Simpsonville (4)
Orangeburg (4)
Lexington (4)
Lancaster (4)
Greenwood (4)
Conway (4)
Clinton (4)
Anderson (4)
Walterboro (3)
Summerville (3)
Seneca (3)
Ridgeland (3)
Mt. Pleasant (3)
Hartsville (3)
Gaffney (3)
Easley (3)
Chesterfield (3)
Beaufort (3)
Winnsboro (2)
All Types
Co-Occurring Mental Health
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Outpatient
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MHN
Medicaid
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Quick answer

South Carolina has 201 verified treatment centers. Medicaid has not been expanded, but facilities offer sliding-scale fees and payment plans. The overdose rate is 38/100k (#15 nationally, above the national average of 33.1). Top cities: Greenville, Charleston, Florence. Need help? Call (833) 546-3513.

Reviewed by RehabHive Editorial Team · Last updated Apr 29, 2026 · Sources: SAMHSA · NIDA · CDC · KFF
The Courage Center-Orangeburg
SC

The Courage Center-Orangeburg

Orangeburg, SC

Co-Occurring Mental Health Verified
Aetna · Anthem · BlueCross BlueShield · Bright Health +20

Situated in the heart of Orangeburg, The Courage Center is a nonprofit dedicated to offering free, peer-led recovery support to adolescents, young adults, and t...

Young Adults Adolescents Recovery Coaching Loved Ones
Holistic Twelve Step Men Women
View Profile → (833) 546-3513
GoForth Recovery
SC

GoForth Recovery

Spartanburg, SC

Residential Rehab Verified
Aetna · Anthem · BlueCross BlueShield · Bright Health +20

GoForth Recovery is a non-profit organization located in Spartanburg, South Carolina, dedicated to supporting men struggling with substance use disorders. The f...

Drug Addiction Men Twelve Step Facilitation
Evidence-Based Gender-Specific Men Men Only
View Profile → (833) 546-3513
LifeStance Health Greenville
SC

LifeStance Health Greenville

Greenville, SC

Outpatient Verified
Aetna · Anthem · BlueCross BlueShield · Bright Health +20

Serving the Taylor, MI community, LifeStance Health Greenville is a trusted local resource for recovery. LifeStance Health has several locations that offer a na...

Depression Outpatient Therapy
Evidence-Based Personalized Treatment Men Men and Women
View Profile → (833) 546-3513
LifeStance Health Rock Hill
SC

LifeStance Health Rock Hill

Rock Hill, SC

Outpatient Verified
Aetna · Anthem · BlueCross BlueShield · Bright Health +20

Serving the Taylor, MI community, LifeStance Health Rock Hill is a trusted local resource for recovery. LifeStance Health has several locations that offer a nat...

Depression Outpatient Therapy
Evidence-Based Personalized Treatment Men Men and Women
View Profile → (833) 546-3513
The Courage Center-Richland
SC

The Courage Center-Richland

Columbia, SC

Co-Occurring Mental Health Verified
Aetna · Anthem · BlueCross BlueShield · Bright Health +20

Located in vibrant Columbia, The Courage Center serves as a nonprofit that provides complimentary, peer-led recovery support for young individuals and their fam...

Young Adults Adolescents Recovery Coaching Loved Ones
Holistic Twelve Step Men Women
View Profile → (833) 546-3513
Chrysalis Center Florence
SC

Chrysalis Center Florence

Florence, SC

Residential Rehab Verified
Aetna · Anthem · BlueCross BlueShield · Bright Health +20

This women’s residential program supports mothers diagnosed with substance use disorders, offering 90-120 days of treatment in a nurturing, family-centered envi...

Drug Addiction Trauma Women only Opioids
Evidence-Based Gender-Specific Women Girls
View Profile → (833) 546-3513
LifeStance Health Cayce
SC

LifeStance Health Cayce

Cayce, SC

Outpatient Verified
Aetna · Anthem · BlueCross BlueShield · Bright Health +20

Serving the Taylor, MI community, LifeStance Health Cayce is a trusted local resource for recovery. LifeStance Health has several locations that offer a nationa...

Depression Outpatient Therapy
Evidence-Based Personalized Treatment Men Men and Women
View Profile → (833) 546-3513
The Lee Center
SC

The Lee Center

Bishopville, SC

Co-Occurring Mental Health Outpatient Verified
Aetna · Anthem · BlueCross BlueShield · Bright Health +20

The Lee Center offers a full range of outpatient programs for substance use, mental health, and co-occurring disorders. They provide prevention, intervention, a...

Alcohol Co-Occurring Disorders Drug Addiction Gambling
Evidence-Based Individual Treatment Men Men and Women
View Profile → (833) 546-3513
Aiken Center
SC

Aiken Center

Aiken, SC

Co-Occurring Mental Health Outpatient Verified
Aetna · Anthem · BlueCross BlueShield · Bright Health +20

Aiken Center supports teens and adults facing challenges with alcohol, drugs, trauma, anxiety, and related mental health needs. Teens ages 12 -18 receive care t...

Alcohol Co-Occurring Disorders Drug Addiction Medication-Assisted Treatment
Evidence-Based Twelve Step Men Men and Women
View Profile → (833) 546-3513
Recovery Centers of America at Greenville
SC
5

Recovery Centers of America at Greenville

Greenville, SC

Co-Occurring Mental Health Detox Verified
Aetna · Anthem · BlueCross BlueShield · Bright Health +20

RCA at Greenville delivers clinically proven care with signature compassion in a peaceful, modern setting designed for connection and healing. They treat substa...

Co-Occurring Disorders Detox Residential Professionals
Evidence-Based Individual Treatment Men Men and Women
View Profile → (833) 546-3513
South Carolina Addiction Treatment
SC
4

South Carolina Addiction Treatment

Simpsonville, SC

Residential Rehab Co-Occurring Mental Health Detox Verified
Aetna · Anthem · BlueCross BlueShield · Bright Health +20

South Carolina Addiction Treatment offers medical detox and residential treatment for substance use in the Greenville area. Treatment is available for alcohol,...

Alcohol Drug Addiction Opioids Detox
Evidence-Based Individual Treatment Men Men and Women
View Profile → (833) 546-3513
Transcendence Treatment Center
SC
4

Transcendence Treatment Center

North Charleston, SC

Outpatient Verified
Aetna · Anthem · BlueCross BlueShield · Bright Health +20

Transcendence Treatment Center is an outpatient addiction treatment center in North Charleston, South Carolina. They offer a range of holistic and trauma-inform...

Alcohol Drug Addiction
Holistic Trauma Informed Men Men and Women
View Profile → (833) 546-3513
Recovery Unplugged South Carolina
SC
5

Recovery Unplugged South Carolina

North Charleston, SC

Co-Occurring Mental Health Outpatient Verified
Aetna · Anthem · BlueCross BlueShield · Bright Health +20

At Recovery Unplugged’s Charleston center, clients find an immersive space to heal from substance use disorders and co-occurring mental health conditions. Throu...

Alcohol Co-Occurring Disorders Drug Addiction Medication-Assisted Treatment
Evidence-Based Holistic Men Men and Women
View Profile → (833) 546-3513
Crossroads Treatment Center Myrtle Beach
SC
4

Crossroads Treatment Center Myrtle Beach

Myrtle Beach, SC

Verified
Aetna · Anthem · BlueCross BlueShield · Bright Health +20

Located near Highways 501 and 17, Crossroads Treatment Center Myrtle Beach offers outpatient opioid treatment for clients across the Grand Strand area, acceptin...

Medication-Assisted Treatment Opioids
Evidence-Based Individual Treatment Men Men and Women
View Profile → (833) 546-3513
American Detox and Residential Treatment Center
SC
4

American Detox and Residential Treatment Center

Chesnee, SC

Residential Rehab Co-Occurring Mental Health Detox Verified
Aetna · Anthem · BlueCross BlueShield · Bright Health +20

Located in Chesnee, South Carolina, this center offers detox and residential treatment for substance addictions and co-occurring mental health disorders. Americ...

First Responders Program Veterans
Individual Treatment Trauma Informed Veterans
View Profile → (833) 546-3513
Crossroads Treatment Center Hartsville
SC
4

Crossroads Treatment Center Hartsville

Hartsville, SC

Verified
Aetna · Anthem · BlueCross BlueShield · Bright Health +20

Located near the Walmart Supercenter and Highway 15, Crossroads Treatment Center Hartsville offers outpatient opioid treatment for clients across Darlington Cou...

Medication-Assisted Treatment Opioids
Evidence-Based Individual Treatment Men Men and Women
View Profile → (833) 546-3513
Crossroads Treatment Center Florence
SC
4

Crossroads Treatment Center Florence

Florence, SC

Verified
Aetna · Anthem · BlueCross BlueShield · Bright Health +20

Located near I-95 and W Lucas Street, Crossroads Treatment Center Florence offers outpatient opioid treatment for clients across Buncombe County, accepting Medi...

Medication-Assisted Treatment Opioids
Evidence-Based Individual Treatment Men Men and Women
View Profile → (833) 546-3513
Crossroads Treatment Center Columbia
SC
4

Crossroads Treatment Center Columbia

Columbia, SC

Outpatient Verified
Aetna · Anthem · BlueCross BlueShield · Bright Health +20

Located near the Williams-Brice Stadium, Crossroads Treatment Center Columbia offers outpatient opioid treatment for clients across Richland and Lexington Count...

Medication-Assisted Treatment Opioids
Evidence-Based Individual Treatment Men Men and Women
View Profile → (833) 546-3513
Sweetgrass Psychiatry Mount Pleasant
SC
4

Sweetgrass Psychiatry Mount Pleasant

Mt Pleasant, SC

Co-Occurring Mental Health Outpatient Verified
Aetna · Anthem · BlueCross BlueShield · Bright Health +20

Located on Johnnie Dodds Boulevard with convenient access to the greater Charleston area, Sweetgrass Psychiatry offers in person and telehealth services for adu...

Depression Transcranial Magnetic Stimulation Virtual Ketamine Therapy
Evidence-Based Holistic Men Men and Women
View Profile → (833) 546-3513
Sweetgrass Psychiatry Isle of Palms
SC
4

Sweetgrass Psychiatry Isle of Palms

Isle of Palms, SC

Co-Occurring Mental Health Outpatient Verified
Aetna · Anthem · BlueCross BlueShield · Bright Health +20

Overlooking the Isle of Palms estuary, Sweetgrass Psychiatry offers in person and virtual services for adults and children including individual, group, and fami...

Depression Transcranial Magnetic Stimulation Virtual Ketamine Therapy
Evidence-Based Holistic Men Men and Women
View Profile → (833) 546-3513
LifeStance Health Mount Pleasant
SC
4

LifeStance Health Mount Pleasant

Mount Pleasant, SC

Outpatient Verified
Aetna · Anthem · BlueCross BlueShield · Bright Health +20

LifeStance Health in Mount Pleasant, SC, is a comprehensive mental health care facility located at 871 Lowcountry Boulevard, Suite 200. This center offers a wid...

Anxiety Depression Virtual
Evidence-Based Personalized Treatment Men Men and Women
View Profile → (833) 546-3513
Sumter Behavioral Health
SC
4

Sumter Behavioral Health

Sumter, SC

Verified
Aetna · Anthem · BlueCross BlueShield · Bright Health +20

Sumter Behavioral Health is an intensive outpatient program (IOP) in Sumter, South Carolina offering evidence-based treatments for substance use and co-occurrin...

View Profile → (833) 546-3513
LifeStance Health Myrtle Beach
SC
4

LifeStance Health Myrtle Beach

Myrtle Beach, SC

Outpatient Verified
Aetna · Anthem · BlueCross BlueShield · Bright Health +20

LifeStance Health in Myrtle Beach, South Carolina, offers comprehensive mental health care services for individuals of all ages. The center provides outpatient...

Anxiety Depression Virtual
Evidence-Based Individual Treatment Men Men and Women
View Profile → (833) 546-3513
LifeStance Health Goose Creek
SC
4

LifeStance Health Goose Creek

Goose Creek, SC

Outpatient Verified
Aetna · Anthem · BlueCross BlueShield · Bright Health +20

LifeStance Health in Goose Creek, SC is a comprehensive mental health care center located at 597 Old Mount Holly Rd, Suite 300. This full-service clinic offers...

Anxiety Depression Virtual
Evidence-Based Personalized Treatment Men Men and Women
View Profile → (833) 546-3513
Charleston Recovery Center
SC
4

Charleston Recovery Center

Hollywood, SC

Residential Rehab Co-Occurring Mental Health Sober Living Verified
Aetna · Anthem · BlueCross BlueShield · Bright Health +20

Charleston Recovery Center is a non-profit organization that operates a residential treatment facility dedicated to adults struggling with alcohol and substance...

Sober Living Twelve Step Facilitation
Twelve Step Spiritual Emphasis Men Men and Women
View Profile → (833) 546-3513
Emend Healthcare
SC
4

Emend Healthcare

Darlington, SC

Outpatient Verified
Aetna · Anthem · BlueCross BlueShield · Bright Health +20

This treatment center offers long-term recovery options by providing residential treatment and outpatient treatment. They believe in the power of tailored recov...

Alcohol Drug Addiction Licensed Primary Mental Health
Evidence-Based Personalized Treatment Men Men and Women
View Profile → (833) 546-3513
The Carolina Center
SC
4

The Carolina Center

Greer, SC

Detox Verified
Aetna · Anthem · BlueCross BlueShield · Bright Health +20

Located in Greer, South Carolina, The Carolina Center caters to adolescents, adults, and senior adults struggling with substance use disorder and acute psychiat...

Drug Addiction Depression Schizophrenia Personality Disorders
Evidence-Based Individual Treatment Men Men and Women
View Profile → (833) 546-3513
Recovery Unplugged Virtual
SC
5

Recovery Unplugged Virtual

North Charleston, SC

Outpatient Verified
Aetna · Anthem · BlueCross BlueShield · Bright Health +20

At Recovery Unplugged’s virtual center, clients find a virtual space to heal from substance use disorders and mental health conditions. Through their innovative...

Alcohol Co-Occurring Disorders Drug Addiction Anxiety
Evidence-Based Holistic Men Men and Women
View Profile → (833) 546-3513
Hammocks On The Edisto
SC
4

Hammocks On The Edisto

Jacksonboro, SC

Residential Rehab Co-Occurring Mental Health Verified
Aetna · Anthem · BlueCross BlueShield · Bright Health +20

Located on the beautiful Edisto River in sunny South Carolina lies Hammocks, a women's recovery center that provides individualized, holistic addiction treatmen...

Alcohol Co-Occurring Disorders Drug Addiction Anxiety
Evidence-Based Holistic Women only
View Profile → (833) 546-3513
Owl's Nest Recovery Community
SC
4

Owl's Nest Recovery Community

Florence, SC

Co-Occurring Mental Health Outpatient Verified
Aetna · Anthem · BlueCross BlueShield · Bright Health +20

The Owl's Nest Recovery Community is a privately owned outpatient treatment center that offers partial hospitalization (PHP), intensive outpatient programing (I...

Alcohol Co-Occurring Disorders Drug Addiction Opioids
Evidence-Based Holistic Men Women
View Profile → (833) 546-3513
Xanadu Healthcare
SC
4

Xanadu Healthcare

Darlington, SC

Detox Verified
Aetna · Anthem · BlueCross BlueShield · Bright Health +20

Xanadu treats chronic drug and alcohol use by addressing physical, mental, emotional, and spiritual issues. They provide gender-specific, holistic, and evidence...

Alcohol Co-Occurring Disorders Drug Addiction
Evidence-Based Holistic Men Women
View Profile → (833) 546-3513
LifeStance Health North Charleston
SC
3

LifeStance Health North Charleston

Charleston, SC

Verified
Aetna · Anthem · BlueCross BlueShield · Bright Health +20

Conveniently located off Interstate 536 on the first floor of the Faber Centre building, LifeStance Health North Charleston is a private therapy practice offeri...

Anxiety Depression Private Therapy
Evidence-Based Individual Treatment Men Men and Women
View Profile → (833) 546-3513
Greenville Transitions Recovery Center
SC
3

Greenville Transitions Recovery Center

Greenville, SC

Co-Occurring Mental Health Outpatient Verified
Aetna · Anthem · BlueCross BlueShield · Bright Health +20

Greenville Transitions unique approach to treating addiction combines evidence-based therapy with adventure activities in an outpatient setting. Designed as the...

Alcohol Drug Addiction Outpatient Adventure Therapy
Evidence-Based Holistic Men Men and Women
View Profile → (833) 546-3513
LifeStance Health Summerville
SC
3

LifeStance Health Summerville

Summerville, SC

Verified
Aetna · Anthem · BlueCross BlueShield · Bright Health +20

Located near local shopping areas, LifeStance Health Summerville is a private therapy practice offering comprehensive mental health care services. Their team of...

Anxiety Depression Private Therapy
Evidence-Based Individual Treatment Men Men and Women
View Profile → (833) 546-3513
LifeStance Health 115 Atrium Way
SC
3

LifeStance Health 115 Atrium Way

Columbia, SC

Verified
Aetna · Anthem · BlueCross BlueShield · Bright Health +20

Located right off Interstate 77, LifeStance Health's 115 Atrium Way clinic is a private therapy practice in Columbia, South Carolina. Their team of master's-lev...

Anxiety Depression Private Therapy
Evidence-Based Individual Treatment Men Men and Women
View Profile → (833) 546-3513
Waypoint Recovery Center
SC
4

Waypoint Recovery Center

Cameron, SC

Co-Occurring Mental Health Outpatient Detox Verified
Aetna · Anthem · BlueCross BlueShield · Bright Health +20

The Waypoint Recovery Center specializes in the treatment of co-occurring medical conditions and substance use disorders. Clients undergo a preliminary clinical...

Co-Occurring Disorders
Evidence-Based Holistic Men Men and Women
View Profile → (833) 546-3513
Marieva Healthcare
SC
4

Marieva Healthcare

Darlington, SC

Residential Rehab Detox Verified
Aetna · Anthem · BlueCross BlueShield · Bright Health +20

Marieva Healthcare’s rehabilitation treatment program treats and releases, with love and care, individuals from their daily battle with addictions and other men...

Depression Eating Disorders Prescription Drugs
Holistic Personalized Treatment Men Women
View Profile → (833) 546-3513
Tulasi Healthcare
SC
4

Tulasi Healthcare

Darlington, SC

Outpatient Detox Verified
Aetna · Anthem · BlueCross BlueShield · Bright Health +20

Based in Gurgaon, Tulasi Healthcare treats clients of all ages with mental health conditions, substance use disorders, and behavioural addictions such as gambli...

Drug Addiction Anxiety Depression Professionals
Evidence-Based Holistic Men Men and Women
View Profile → (833) 546-3513
Promises Healthcare
SC
3

Promises Healthcare

Darlington, SC

Co-Occurring Mental Health Verified
Aetna · Anthem · BlueCross BlueShield · Bright Health +20

Promises Healthcare is one of the most sought-after service providers in Singapore for mental health treatment and rehabilitation thanks to a staff of diversifi...

Drug Addiction Depression Adolescents Personality Disorders
Evidence-Based Holistic Men Women
View Profile → (833) 546-3513
LifeStance Health Charleston
SC
2

LifeStance Health Charleston

Charleston, SC

Verified
Aetna · Anthem · BlueCross BlueShield · Bright Health +20

LifeStance Health Charleston is a private therapy practice located approximately 6 miles west of downtown Charleston, South Carolina. Their team of licensed men...

Anxiety Depression Private Therapy
Evidence-Based Individual Treatment Men Men and Women
View Profile → (833) 546-3513
New Life Center
SC

New Life Center

Allendale, SC

Co-Occurring Mental Health Outpatient Verified
Aetna · Anthem · BlueCross BlueShield · Bright Health +20

Government-funded center for all ages with substance use and mental health services, trauma counseling, and medication-assisted treatment options.

Men Women
View Profile → (833) 546-3513
SC

Anderson/Oconee/Pickens Comm MH Oconee Clinic

Seneca, SC

Co-Occurring Mental Health Outpatient Verified
Aetna · Anthem · BlueCross BlueShield · Bright Health +20

Community mental health center providing outpatient services for all ages, specializing in co-occurring mental health and substance use disorders.

Men Women
View Profile → (833) 546-3513
SC

Anderson/Oconee/Pickens Comm MH Pickens Clinic

Easley, SC

Co-Occurring Mental Health Outpatient Verified
Aetna · Anthem · BlueCross BlueShield · Bright Health +20

Integrative outpatient center providing trauma-informed care for adults, seniors, and young adults with mental health and substance use disorders.

Men Women
View Profile → (833) 546-3513
SC

Anderson/Oconee/Pickens MH Center Anderson Adult Clinic

Anderson, SC

Co-Occurring Mental Health Outpatient Verified
Aetna · Anthem · BlueCross BlueShield · Bright Health +20

Community mental health center providing comprehensive outpatient services including therapy, case management, crisis intervention, and treatment for co-occurri...

Men Women
View Profile → (833) 546-3513
SC

Catawba Community Mental Health Center Chester Clinic

Chester, SC

Co-Occurring Mental Health Outpatient Verified
Aetna · Anthem · BlueCross BlueShield · Bright Health +20

Community mental health center offering outpatient services for adults, children, and seniors with a focus on co-occurring mental health disorders.

Men Women
View Profile → (833) 546-3513
SC

Catawba Community Mental Health Center York Adult Services

Rock Hill, SC

Co-Occurring Mental Health Outpatient Verified
Aetna · Anthem · BlueCross BlueShield · Bright Health +20

Community mental health center offering outpatient services for adults with serious mental illness and co-occurring substance use disorders. LGBT-friendly and t...

Men Women
View Profile → (833) 546-3513
SC

Children and Adolescent Services William E Pascoe Clinic

Anderson, SC

Co-Occurring Mental Health Outpatient Verified
Aetna · Anthem · BlueCross BlueShield · Bright Health +20

Children and Adolescent Services providing comprehensive outpatient care with Medicaid coverage, individual and group therapy, education services, and mentoring...

Adolescents Children
View Profile → (833) 546-3513
SC

Clear Skye Treatment Center Gaffney

Gaffney, SC

Outpatient Verified
Aetna · Anthem · BlueCross BlueShield · Bright Health +20

Clear Skye Treatment Center in Gaffney, SC, delivers comprehensive outpatient services for those facing substance use challenges. Their therapeutic repertoire i...

Men Women
View Profile → (833) 546-3513
SC

Coastal Empire Community MH Beaufort Mental Health Clinic

Beaufort, SC

Co-Occurring Mental Health Outpatient Verified
Aetna · Anthem · BlueCross BlueShield · Bright Health +20

Coastal Empire Community Mental Health Clinic in Varnville, SC, is committed to providing compassionate care for individuals facing mental health and substance...

Men Women
View Profile → (833) 546-3513
SC

Coastal Empire Community MH Colleton County Mental Health Clinic

Walterboro, SC

Co-Occurring Mental Health Outpatient Verified
Aetna · Anthem · BlueCross BlueShield · Bright Health +20

Coastal Empire Community MH Colleton County Mental Health Clinic in Varnville, SC, specializes in an integrated approach to mental health and substance use trea...

Men Women
View Profile → (833) 546-3513

Insurance accepted in South Carolina

Under the federal Mental Health Parity Act, most South Carolina centers accept major plans. Tap a carrier for coverage details, or verify your benefits free in under 5 minutes.

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Addiction Treatment in South Carolina: What You Need to Know

South Carolina has 201 SAMHSA-verified treatment facilities serving a population of 5,373,000. That's approximately 3.7 facilities per 100,000 residents. The state's drug overdose death rate of 38 per 100,000 is above the national average of 33.1 — ranking #15 nationally. With 1,380 opioid-related deaths reported annually, access to evidence-based treatment programs remains critical.

South Carolina overdose & addiction statistics

South Carolina reports 1,380 opioid-related deaths annually with an overdose rate of 38 per 100,000 residents — above the 33.1 national average by 15%. Substance use disorder affects approximately 6.1% of South Carolina adults, compared with a 7.2% national rate. Provisional mortality data are tracked by CDC WONDER, and the National Institute on Drug Abuse publishes the trends behind them. Illicitly manufactured fentanyl now drives the majority of U.S. opioid deaths, which is why rapid access to detox and medication-assisted treatment matters for South Carolina residents.

Levels of care available in South Carolina

South Carolina facilities offer the full continuum of care recognized by the American Society of Addiction Medicine (ASAM). The right starting level depends on the substance, severity, medical risk, and home environment — a free assessment matches you to the appropriate intensity.

ProgramDurationCost RangeBest For
Medical Detox5–10 days$1,000–$5,000Alcohol, opioid, benzo withdrawal
Inpatient Rehab28–90 days$6,000–$30,000Severe addiction, co-occurring disorders
PHP (Partial Hospitalization)2–4 weeks$3,000–$10,000Step-down from inpatient, intensive support
IOP (Intensive Outpatient)2–4 months$3,000–$10,000Work/school compatibility, 9-20 hrs/week
Outpatient3–12 months$1,400–$10,000Mild-moderate, stable housing
MAT6–24+ months$5,000–$15,000/yrOpioid use disorder, relapse prevention

How much does rehab cost in South Carolina — and how to pay

Out-of-pocket prices range from about $1,000 for a short medical detox to $30,000+ for 90-day residential care, but most South Carolina residents pay a small fraction of that. Under the federal Mental Health Parity and Addiction Equity Act, commercial plans and Medicaid must cover substance use treatment at parity with medical care. Common ways to pay include private insurance, limited Medicaid for eligible groups, sliding-scale fees, monthly payment plans, and state-funded program slots. Call (833) 546-3513 for a free, confidential benefits check.

Insurance & Medicaid coverage in South Carolina

South Carolina has not expanded Medicaid under the ACA, which limits publicly funded treatment access for low-income adults without dependent children. However, traditional Medicaid still covers some addiction treatment services for eligible populations (pregnant women, children, individuals with disabilities). Many of South Carolina's 201 facilities offer alternative payment options: sliding-scale fees based on income, payment plans, state-funded program slots, and private insurance acceptance. The Mental Health Parity Act requires most private insurers to cover SUD treatment at the same level as medical/surgical care.

Free & low-cost treatment options in South Carolina

No-cost and reduced-cost help exists for South Carolina residents without insurance. State-licensed providers receive federal Substance Abuse Block Grant funding administered through SAMHSA to offer free or sliding-scale care, prioritizing pregnant women, people who inject drugs, and parents. To find verified options near you, search the official FindTreatment.gov locator, call SAMHSA's National Helpline at 1-800-662-4357 (free, 24/7, English/Spanish), or dial 211 for local community resources. Faith-based programs and county mental-health authorities also provide low- or no-cost slots.

How to choose a rehab in South Carolina

Quality varies, so weigh five factors before committing: (1) Accreditation — look for CARF or Joint Commission accreditation and state licensure; (2) Evidence-based care — therapies such as CBT, DBT, motivational interviewing, and MAT, consistent with the NIDA Principles of Effective Treatment; (3) Level-of-care match — an ASAM assessment so you neither under- nor over-treat; (4) Dual-diagnosis capacity for co-occurring depression, anxiety, or trauma; and (5) Aftercare — discharge planning, alumni support, and relapse-prevention. Browse verified South Carolina centers and filter by accreditation, program, and insurance.

Laws & harm reduction in South Carolina

South Carolina has a 911 Good Samaritan law that shields people who call for help during an overdose from certain drug-possession charges, removing a major barrier to calling 911. Naloxone (Narcan), the opioid-overdose reversal medication, is available via standing order, meaning most residents can obtain it without an individual prescription; the CDC's Stop Overdose program explains how to use it. Anyone in crisis can reach the 988 Suicide & Crisis Lifeline by call or text, 24/7.

Where to find help in South Carolina

Treatment facilities in South Carolina are concentrated in urban areas, with Greenville leading with 16 centers, followed by Charleston (11) and Florence (9). For residents in rural areas, telehealth addiction counseling and out-of-area programs provide alternatives. Browse our full South Carolina directory to filter by city, treatment type, and insurance accepted.

Medical Disclaimer: This page provides educational information and is not a substitute for professional medical advice. If experiencing a medical emergency, call 911. For immediate treatment guidance, contact SAMHSA's National Helpline at 1-800-662-4357 (free, confidential, 24/7, English/Spanish).

Last updated: March 2026 · Sourced from SAMHSA, CDC WONDER, KFF

Check Your Insurance Coverage in South Carolina

Private insurance and state programs available. Verify your benefits — free and confidential.

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Understanding Treatment Options in South Carolina

Effective addiction treatment requires at least 90 days in a structured program, according to NIDA research. In South Carolina, treatment centers offer multiple levels of care along a continuum — from medically supervised detoxification (3-10 days) through residential inpatient programs (30-90 days), partial hospitalization (PHP), intensive outpatient (IOP), and standard outpatient counseling.

Medication-assisted treatment (MAT) with buprenorphine, methadone, or naltrexone reduces opioid overdose deaths by 50% (CDC data). Many South Carolina facilities now integrate MAT with behavioral therapies including cognitive-behavioral therapy (CBT), dialectical behavior therapy (DBT), and motivational interviewing for comprehensive dual-diagnosis care.

Treatment centers that match program intensity to individual patient needs achieve the strongest long-term recovery outcomes, according to NIH research. Most insurance plans cover substance abuse treatment under federal parity law. under the Mental Health Parity and Addiction Equity Act, most commercial plans and Medicaid must cover substance abuse treatment at parity with medical care.

Sources: NIDA Principles of Drug Addiction Treatment (4th Ed.), CDC MMWR Vol. 72, NIH National Institute on Alcohol Abuse and Alcoholism

Verified Treatment Centers 201
Overdose Death Rate 38 per 100,000 (#15 nationally)
Annual Opioid Deaths 1,380
Medicaid Expansion Not expanded
Naloxone Access standing order
24/7 Helpline (833) 546-3513 — free verification

Treatment FAQ — South Carolina

How many rehab centers are in South Carolina?
South Carolina has 201 SAMHSA-verified treatment facilities, including inpatient, outpatient, detox, and MAT programs. The largest concentration is in Greenville with 16 centers.
How much does rehab cost in South Carolina?
Outpatient: $5,000–$10,000. IOP: $3,000–$10,000. Residential: $10,000–$30,000+ for 30 days. Many facilities offer sliding-scale fees or payment plans. Call (833) 546-3513 for free insurance verification.
Does Medicaid cover rehab in South Carolina?
South Carolina has not expanded Medicaid. Traditional Medicaid covers some services for eligible populations. Many facilities offer alternative payment options.
What types of treatment are available in South Carolina?
Programs include: medical detox (5–10 days), inpatient/residential (28–90 days), PHP (6+ hours daily), IOP (9–20 hours/week), standard outpatient (1–2 sessions/week), and MAT (buprenorphine, methadone, naltrexone).
Are there free rehab centers in South Carolina?
Yes. SAMHSA-funded facilities provide sliding-scale services. State behavioral health programs serve uninsured residents. Some nonprofit/faith-based programs offer free treatment. Call (833) 546-3513 for help.
What is the overdose crisis in South Carolina?
South Carolina ranks #15 nationally with 38/100k overdose deaths (national avg: 33.1). Approximately 1,380 opioid deaths/year. Good Samaritan law protects callers. Naloxone: standing order.
Can I travel to South Carolina for rehab?
Yes. South Carolina (South region) welcomes out-of-state patients. Many insurance plans cover out-of-network treatment. Distance from triggers can benefit recovery. Call (833) 546-3513 to verify coverage.
How do I choose the right rehab in South Carolina?
Look for: (1) CARF/Joint Commission accreditation, (2) evidence-based therapies (CBT, DBT, MI), (3) insurance acceptance, (4) specializations (dual diagnosis, gender-specific), (5) aftercare planning. Call (833) 546-3513 for personalized guidance.
How much does rehab cost in South Carolina without insurance?
Without insurance, rehab costs approximately $1,000-$3,000/month for outpatient, $5,000-$20,000 for 30-day residential, and $12,000-$60,000 for 90-day inpatient. Sliding-scale fee programs are also available. Call (833) 546-3513 for options.
Does South Carolina Medicaid cover residential rehab?
South Carolina has not expanded Medicaid, but state-funded programs and sliding-scale facilities are available. Call (833) 546-3513 for help.
What are the best-rated rehab centers in South Carolina?
South Carolina has 201 SAMHSA-verified centers. Quality depends on JCAHO/CARF accreditation, patient outcomes, and staff credentials. Browse our directory or call (833) 546-3513 for personalized recommendations.

Looking in Nearby States?

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