Treatment Guide · Evidence-Based Care

Medication-Assisted Treatment (MAT) for Addiction Recovery

Medication-Assisted Treatment combines FDA-approved medications such as buprenorphine (Suboxone), methadone, or naltrexone (Vivitrol) with counseling and behavioral therapies. MAT is clinically proven to reduce opioid us...

Last reviewed Apr 29, 2026 SAMHSA & NIDA sourced RehabHive Editorial Team
Duration
Ongoing (12+ months recommended)
Typical cost
$5,000 - $15,000/year
Insurance
Required to be covered under ACA
Success rate
60-75%
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Overview

Medication-Assisted Treatment combines FDA-approved medications such as buprenorphine (Suboxone), methadone, or naltrexone (Vivitrol) with counseling and behavioral therapies. MAT is clinically proven to reduce opioid use, prevent overdose deaths, decrease criminal activity, and improve treatment retention rates.

What the Research and Authorities Say

Medication-Assisted Treatment is endorsed by SAMHSA as the gold standard for opioid and alcohol use disorder. NIDA research shows MAT reduces opioid overdose deaths by more than 50%, cuts illicit opioid use by 40-60%, and increases treatment retention by two to four times compared to counseling alone. The FDA has approved three medications for opioid use disorder — buprenorphine (Suboxone), methadone, and naltrexone (Vivitrol) — and four for alcohol use disorder. The ASAM National Practice Guideline recommends medication as first-line care; withholding it without clinical justification is considered below the standard of care.

Who Is It For?

MAT is most effective for individuals with opioid use disorder (heroin, fentanyl, prescription painkillers) or alcohol use disorder. It stabilizes brain chemistry, blocks euphoric effects, and relieves cravings so the person can focus on recovery.

What Does It Include?

  • Comprehensive medical assessment
  • FDA-approved medications
  • Individual and group counseling
  • Regular drug screening
  • Psychiatric support
  • Care coordination
  • Peer support and recovery coaching
  • Ongoing monitoring and dosage adjustments

Frequently Asked Questions

What is medication-assisted treatment (mat)?

Medication-Assisted Treatment combines FDA-approved medications such as buprenorphine (Suboxone), methadone, or naltrexone (Vivitrol) with counseling and behavioral therapies. MAT is clinically proven to reduce opioid use, prevent overdose deaths, decrease criminal activity, and improve treatment retention rates.

Who should consider medication-assisted treatment (mat)?

MAT is most effective for individuals with opioid use disorder (heroin, fentanyl, prescription painkillers) or alcohol use disorder. It stabilizes brain chemistry, blocks euphoric effects, and relieves cravings so the person can focus on recovery.

How long does medication-assisted treatment (mat) last?

Typical duration is Ongoing (12+ months recommended). Length should be individualized based on clinical assessment and progress.

How much does medication-assisted treatment (mat) cost?

Average cost is $5,000 - $15,000/year. Required to be covered under ACA. Many facilities offer sliding-scale fees. Call (833) 546-3513 to verify coverage.

What is the success rate?

Success rates are approximately 60-75%. Success improves with longer treatment, aftercare, and addressing co-occurring disorders.

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Medical Disclaimer

This guide is for informational purposes only and does not constitute medical advice. Treatment decisions should be made with a qualified healthcare provider. For immediate help, call SAMHSA National Helpline 1-800-662-HELP (4357) or 911 in an emergency. For confidential benefits verification, call (833) 546-3513.

Find Medication-Assisted Treatment (MAT) by state

Browse verified medication-assisted treatment (mat) programs by location.

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Verified providers

50 Centers Offering Medication-Assisted Treatment (MAT)

SAMHSA-verified facilities providing medication-assisted treatment (mat) programs. Listed alphabetically by state. Call (833) 546-3513 to verify coverage at any center.

True North Recovery Wasilla AK

True North Recovery Wasilla

Wasilla, AK

True North Recovery Fairbanks AK

True North Recovery Fairbanks

Fairbanks, AK

Banyan Alaska AK

Banyan Alaska

Wasilla, AK

Anchorage Comprehensive Treatment Center AK

Anchorage Comprehensive Treatment Center

Anchorage, AK

Community Medical Services Anchorage AK

Community Medical Services Anchorage

Anchorage, AK

Community Medical Services Wasilla AK

Community Medical Services Wasilla

Wasilla, AK

AppleGate Recovery Opelika AL

AppleGate Recovery Opelika

Opelika, AL

Bradford Health Huntsville Outpatient AL

Bradford Health Huntsville Outpatient

Huntsville, AL

MedMark Treatment Centers Oxford AL

MedMark Treatment Centers Oxford

Oxford, AL

Genesis Medical Detox Alabama AL

Genesis Medical Detox Alabama

Muscle Shoals, AL

New Season Treatment Center - Tri County AL

New Season Treatment Center - Tri County

Birmingham, AL

A Reprieve for Women AL

A Reprieve for Women

Tuscaloosa, AL

AppleGate Recovery Decatur AL

AppleGate Recovery Decatur

Decatur, AL

Mobile Metro Treatment Center AL

Mobile Metro Treatment Center

Mobile, AL

Gateway Recovery Center AL

Gateway Recovery Center

Birmingham, AL

MedMark Treatment Centers Dothan AL

MedMark Treatment Centers Dothan

Newton, AL

Gateway Recovery Center Brooklyn Park AL

Gateway Recovery Center Brooklyn Park

Birmingham, AL

Bradford Health Florence Outpatient AL

Bradford Health Florence Outpatient

Florence, AL

Bradford Health Montgomery Outpatient AL

Bradford Health Montgomery Outpatient

Montgomery, AL

Montgomery Metro Treatment Center AL

Montgomery Metro Treatment Center

Montgomery, AL

Pathway Healthcare Birmingham AL

Pathway Healthcare Birmingham

Birmingham, AL

Pathway Healthcare Huntsville AL

Pathway Healthcare Huntsville

Huntsville, AL

Bradford at Madison AL

Bradford at Madison

Madison, AL

Bradford Health Mobile Outpatient AL

Bradford Health Mobile Outpatient

Mobile, AL

Birmingham Metro Treatment Center AL

Birmingham Metro Treatment Center

Birmingham, AL

AppleGate Recovery Jasper AL

AppleGate Recovery Jasper

Jasper, AL

AppleGate Recovery Tuscaloosa AL

AppleGate Recovery Tuscaloosa

Tuscaloosa, AL

AppleGate Recovery Birmingham AL

AppleGate Recovery Birmingham

Birmingham, AL

Clinic 5 AL

Clinic 5

Rainbow City, AL

Bradford Health Birmingham Outpatient AL

Bradford Health Birmingham Outpatient

Birmingham, AL

Huntsville Metro Treatment Center AL

Huntsville Metro Treatment Center

Huntsville, AL

The Stepping Stone at White River Medical Center AR

The Stepping Stone at White River Medical Center

Batesville, AR

AppleGate Recovery El Dorado AR

AppleGate Recovery El Dorado

El Dorado, AR

The Haven Detox - West Memphis AR

The Haven Detox - West Memphis

West Memphis, AR

The Haven Detox - Little Rock AR

The Haven Detox - Little Rock

Little Rock, AR

Rivendell Behavioral Health AR

Rivendell Behavioral Health

Benton, AR

Vantage Point of Northwest Arkansas AR

Vantage Point of Northwest Arkansas

Fayetteville, AR

Conway Behavioral Health AR

Conway Behavioral Health

Conway, AR

Springwoods Behavioral Health AR

Springwoods Behavioral Health

Fayetteville, AR

MedMark Treatment Centers Springdale AR

MedMark Treatment Centers Springdale

Springdale, AR

Valley Behavioral Health System AR

Valley Behavioral Health System

Barling, AR

Desert Mountain Health AZ

Desert Mountain Health

Scottsdale, AZ

Virtue Recovery Detox Sun City West AZ

Virtue Recovery Detox Sun City West

Sun City West, AZ

Community Medical Services Cactus Road - Phoenix AZ

Community Medical Services Cactus Road - Phoenix

Phoenix, AZ

Touch Angels Behavioral Health AZ

Touch Angels Behavioral Health

Gilbert, AZ

Tucson VA Medical Center AZ

Tucson VA Medical Center

Tucson, AZ

Recovia Grant Road - Eastside AZ

Recovia Grant Road - Eastside

Tucson, AZ

Horizon Health and Wellness Adult Program Casa Grande AZ

Horizon Health and Wellness Adult Program Casa Grande

Casa Grande, AZ

Agave Ridge Behavioral Health Hospital AZ

Agave Ridge Behavioral Health Hospital

Mesa, AZ

Sunlight Medical Services AZ

Sunlight Medical Services

Glendale, AZ

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